2014

Children's Hospital that is home to Sheikh Zayed Institute is ranked as one of the Best in US, The National, June 16, 2014

Mobile Phone App Could Help Detect Down Syndrome, Voice of America, April 24, 2014

Video: 3D Printing Technology for Medical Use, The National, April 22, 2014

The Sheikh Zayed Institute in Washington Treats More Than 80,000 Children in 5 Years, Al Ittihad, April 20, 2014

A Million Dollars From the Mohammed bin Zayed Family and Abdulla bin Zayed Family for the Sheikh Zayed Institute for the Development of Pediatric Surgery in Washington, Al Ittihad, April 19, 2014

How Down Syndrome Could Soon Be Diagnosed With A Simple Smartphone Photo, The National, April 14, 2014

UAE Link With DC Hospital Helps Everyone, The National, April 9, 2014

How Zayed's Legacy Still Gives New Hope to Sick Children, The National, Apri 9, 2014

David Ignatius: At Children's National Hospital, Philanthropy with a Wallop, Washington Post, March 28, 2014

The Sheikh Zayed Institute for Pediatric Surgical Innovation Showcases Latest in Pediatric Surgery At United States Congress, Abu Dhabi City Guide, March 18, 2014

3D Printing, Dubai One Tv, March 18, 2014

2013

Media Videos, 2013

Paediatric Innovation Award Announced, The Gulf Today, January 28, 2013

Sheikh Zayed Institute for Pediatric Surgical Innovation To Lead Plans To Award $250,000 For Innovative Pediatric Medical Devices, Abu Dhabi City Guide, January 27, 2013

Power Player of the Week: 3D Printer, Fox News Sunday, January 19, 2013

Doctors Using 3D Printers to Create Organ Replicas, NBC4, December 11, 2013

Medical Research Breakthroughs at Abu Dhabi-funded Sheikh Zayed Institute in Washington DC, The National, October 25, 2013

Research is Vital in Push Towards 2030, The National, October 19, 2013

Sheikh Zayed Institute at Children's National Receives US FDA Grant to Form Pediatric Device Innovation Consortium, Zawya, October 12, 2013

Abu Dhabi Urban Planning Council host delegration from US-based Children's National Medical Center, AMEInfo.com, September 9, 2013

Sheikh Zayed Institute: where bright young minds hang out, GulfNews.com, August 18, 2013

UAE Varsity Students on Summer of Discovery in USA, GulfNews.com, August 18, 2013

Innovations in Treating Kids, PainResource.com, July 25 2013

3D Printers Help Heart Surgeons, Voice of America, July 30, 2013

Student Innovators and 3D Printing, Sky News Arabia, July 9, 2013

Children Living With Constant and Incurable Pain, BBC News, July 5, 2013

Five Khalifa University students represent UAE at Children's National Medical Center's elite bio-medical innovation program, Zawya, July 2, 2013

UAE Embassy in Washington hosted Abu Dhabi University Business Students, UAE Interact, July 7, 2013

Five UAE women who hope to make a difference, The National, June 9, 2013

Technology helps children heal, CNN Newsroom, May 17, 2013

3D Tech Making Surgery More Accurate, Fox Business, May 15, 2013

To help solve challenging cardiac problems, doctors at Children's press 'print,' The Washington Post, May 13, 2013

Specialists See Tools toTreat Pain in Video Games, The New York Times, April 20, 2013

Children's team treats pain with technology, integrative approaches, WTOP, April 19, 2013

At Children's Hospital, video games are part of the prescription, The Washington Post, April 18, 2013

A New Way To Treat Children With Chronic Pain, Scoop San Diego, April 18, 2013

Children's National Medical Center opens new Pain Medicine Care Complex, World Interior Design Network, April 8, 2013

Kinect-enabled games used in pain care for kids, GMA News Online, April 5, 2013

Video Games Help Treat Kids With Chronic Pain, Mashable, April 4, 2013

The Healing Power of Video Games, Youth Today, April 4, 2013

The National Spotlights Children’s National Medical Center’s Innovative Sheikh Zayed Pain Medicine Initiative, The National, February 11, 2013


Children’s National Saves UAE Girl From Life-Threatening Congenital Heart Disease, The National, February 11, 2013


2014

Children's National Sheikh Zayed Institute Executives Cite 'Challenges' to Pediatric Device Development, September 11, 2014

Children's National Health System Announces Competition: "Make Your Medical Device Pitch for Kids!", August 29, 2014

Children's National Health System Hosts Second Annual Innovation Symposium Featuring FDA Commissioner as Keynote Speaker, August 28, 2014

Sheikh Zayed Institute Leads Consortium Planning $250,000 Awards for Innovative Pediatric Medical Devices, January 13, 2014

2013

Sheikh Zayed Institute at Children's National Medical Receives FDA Grant To Form Pediatric Device Innovation Consortium, September 26, 2013

Children's National To Issue Concensus Paper on Pediatric Surgical Innovation and Device Development, August 8, 2013

Children’s National Presents First Sheikh Zayed Prize for Pediatric Surgical Innovation, June 14, 2013

U.S.News & World Report: Children’s National Medical Center Again Ranked among Best Children’s Hospitals, June 11, 2013

Children's National to Host Symposium on Medical Device Development, May 21, 2013

Children's National to Advance Dialogue for Pediatric Medical Innovations, April 19, 2013

Children's National Medical Center Unveils New Pain Medicine Care Complex, April 3, 2013

2012

Inpatient Bariatric Procedures for Adolescents Appear to Have Plateaued Since 2003; Childhood Obesity Still on the Rise- December 18, 2012

Inpatient bariatric procedures among adolescents have plateaued since 2003, according to a study by researchers at Children’s National Medical Center, published Online First by Archives of Pediatrics & Adolescent Medicine, a JAMA Network publication.


Experts from Children’s National and Sheikh Zayed Institute Focus on Innovations in Pediatric Care at World Health Care Congress Middle East - December 13, 2012
Experts from Children’s National Medical Center and its Sheikh Zayed Institute for Pediatric Surgical Innovation participated in the 3rd Annual World Health Care Congress Middle East this week in Abu Dhabi.


Children’s National Health System

Sheikh Zayed Campus for Advanced Children’s Medicine

111 Michigan Avenue, NW
Washington, DC 20010

Main: 202-476-4500
Patient Report: 202-476-5000

InnovationInstitute@childrensnational.org

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Rohan Fernandes, PhD

Biography

 

Rohan Fernandes, PhD joined the Institute as an Assistant Professor in the Bioengineering Initiative in December 2011. Dr. Fernandes’ research interests include developing multifunctional nanoparticles for theranostics (i.e. simultaneous therapy and diagnostics) of pediatric cancers and inflammatory diseases.

Dr. Fernandes’ current research focuses on repurposing Prussian blue (an ancient dye) as an MRI contrast agent, a disease site-specific fluorescent “paint”, a drug delivery agent, and as an agent for laser-induced photothermal ablation of tumors. Dr. Fernandes’ group is currently testing these novel capabilities of Prussian blue in preclinical models of pediatric cancers and inflammatory diseases. His group closely collaborates with investigators at Children’s, Howard University, and the University of Maryland. Dr. Fernandes completed his PhD in Bioengineering from the University of Maryland in 2008. After his PhD, Dr. Fernandes completed his Postdoctoral Fellowship from Johns Hopkins University in 2011.

 

Publications

Journal

1.      Fernandes R, Wu LQ, Chen TH, Yi HM, Rubloff GW, Ghodssi R, Bentley WE and Payne GF, “Electrochemically induced deposition of a polysaccharide hydrogel onto a patterned surface,” Langmuir, Vol. 19, No. 10, 4058-4062, 2003.

2.      Fernandes R, Yi HM, Wu LQ, Rubloff GW, Ghodssi R, Bentley WE and Payne GF. “Thermo-biolithography: a technique for patterning nucleic acids and proteins,” Langmuir, Vol. 20, No. 3, 906-913, 2004.

3.      Fernandes R, Tsao CY, Hashimoto Y, Wang L, Wood TK, Payne GF and Bentley WE. “Magnetic nanofactories: localized synthesis and delivery of quorum-sensing signaling molecule autoinducer-2 to bacterial cell surfaces,” Metabolic Engineering, Vol. 9, No. 2, 228-239, 2007.

4.      Fernandes R and Bentley WE. “AI-2 biosynthesis module in a magnetic nanofactory alters bacterial response via localized synthesis and delivery,” Biotechnology & Bioengineering, Vol. 102, No. 2, 390-399, 2009.

5.      Wu HC, Shi XW, Tsao C, Lewandowski AT, Fernandes R, Hung CW, DeShong P, Kobatake E, Valdes JJ, Payne GF and Bentley WE. “Biofabrication of antibodies and antigens via IgG-binding domain engineered with activatable pro-tag,” Biotechnology & Bioengineering, Vol. 103, No. 2, 231-240, 2009.

6.      Koev ST, Fernandes R, Bentley WE and Ghodssi R. “A cantilever sensor with integrated optical readout for detection of enzymatically produced homocysteine,” IEEE Transactions on Biomedical Circuits and Systems, Vol. 3, No. 6, 415-423, 2009.

7.      Fernandes R and Gracias DH. “Toward a miniaturized mechanical surgeon,” Materials Today, Vol. 12, No. 10, 14-20, 2009.

8.      Fernandes R, Roy V, Wu HC and Bentley WE. “Engineered biological nanofactories trigger quorum sensing response in targeted bacteria,” Nature Nanotechnology, Vol. 5, No. 3, 213-217, 2010.

9.      Roy V, Fernandes R, Tsao C and Bentley WE. “Cross species quorum quenching using a native AI-2 processing enzyme,” ACS Chemical Biology, Vol. 5, No. 2, 223-232, 2010.

10.   Fernandes R, Luo XL, Tsao C, Payne GF, Ghodssi R, Rubloff GW and Bentley WE. “Biological nanofactories facilitate spatially selective capture and manipulation of quorum sensing bacteria in a bioMEMS device,” Lab on a Chip, Vo. 10, No. 9, 1128-1143, 2010 (Featured on the inside front cover).

11.   James T, Cho J-H, Fernandes R, Randhawa JS and Gracias DH. “A one-step etching method to produce gold nanoparticle coated silicon microwells and microchannels,” Analytical & Bioanalytical Chemistry, Vol. 398, No. 7-8, 2949-2954, 2010.

12.   Hebert CG, Gupta A, Fernandes R, Tsao CY, Valdes JJ and Bentley WE. “Biological nanofactories target and activate epithelial cell surfaces for modulating bacterial quorum sensing and interspecies signaling,” ACS Nano, Vol. 4, No. 11, 6923-6931, 2010.

13.   Azam A, Laflin KE, Jamal M, Fernandes R and Gracias DH. “Self-folding micropatterned polymeric containers,” Biomedical Microdevices, Vol. 13, No. 1, 51-58, 2011.

14.   Fernandes R, Zuniga M, Sassine FR, Karakoy M and Gracias DH. “Enabling cargo-carrying bacteria via surface attachment and triggered release,” Small, Vol. 7, No. 5, 588-592, 2011.

15.   Fernandes R and Gracias DH. “Self-folding polymeric containers for encapsulation and delivery of drugs,” Advanced Drug Delivery Reviews, Vol. 64, No. 14, 1579-1589, 2012.

16.   Gupta A, Terrell JL, Fernandes R, Dowling MB, Payne GF, Raghavan SR and Bentley WE. ““Sense and Respond” Activity to Chitosan-Alginate Capsules To Manipulate Bacterial Quorum Sensing,” Biotechnology & Bioengineering, Vol. 110, No. 2, 552-562, 2013.

17.   Jamal M, Kadam SS, Xiao R, Jivan F, Onn TM, Fernandes R, Nguyen TD and Gracias DH. “Bio-origami hydrogel scaffolds comprised of photocrosslinked PEG bilayers,” Advanced Healthcare Materials, Vol. 2, No. 8, 1142-1150, 2013.

18.   Dumont MF, Hoffman HA, Yoon PRS, Conklin LS, Saha SR, Paglione J, Swe RW and Fernandes R*. “Biofunctionalized Gadolinium-Containing Prussian Blue Nanoparticles as Multimodal Molecular Imaging Agents,” Bioconjugate Chemistry, Vol. 25, No. 1, 129-137, 2014.

19.   Dumont MF, Yadavilli S, Sze RW, Nazarian J and Fernandes R*. “Manganese-containing Prussian blue nanoparticles for imaging of pediatric brain tumors,” International Journal of Nanomedicine, DOI: 10.2147/IJN.S63472, 2014.

*indicates senior/corresponding author

Conference

1.      Koev ST, Fernandes R, Bentley WE and Ghodssi R. “A microcantilever sensor with integrated optical readout for antimicrobial drug discovery,” 15th International Conference on Solid-State Sensors, Actuators, and Microsystems, Denver, CO, 2009.

2.      Fernandes R, James T, Zuniga MC, Li H, Ngan S and Gracias DH. “Assembling backpacking bacteria for diagnostics and therapeutics,” 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS), Seattle, WA, 2011.

 

Awarded Patents

1.      Payne GF, Rubloff GW, Yi HM, Fernandes R, Wu LQ, Ghodssi R, Bentley WE. “Biolithographical deposition and materials and devices formed therefrom,” U.S. Patent 7,820,227.

2.      Payne GF, Wu LQ, Ghodssi R, Bentley WE, Rubloff GW, Yi HM, Fernandes R, Chen TH, Small DA. “Controlled electrochemical deposition of polysaccharide films and hydrogels, and materials formed therefrom,” U.S. Patent 7,883,615.

 

Patent Applications

1.      Fernandes R, Dumont MF, Sze RW, Conklin LS, Jaiswal JK, Hoffman HA. “Prussian-blue inspired constructs for multimodal imaging and therapy.” US Patent Application No. 14/213380